Ashwagandha
Withania somnifera
Ashwagandha (Withania somnifera) is a powerful adaptogen that has been a cornerstone of Ayurvedic medicine for over 3,000 years. Classified as a 'rasayana' (rejuvenator) in the Ayurvedic tradition, it is one of the most clinically studied adaptogens with multiple human randomized controlled trials supporting its effects on stress, anxiety, cognitive function, testosterone levels, and physical performance. The root contains withanolides — steroidal lactones that modulate the hypothalamic-pituitary-adrenal (HPA) axis, the body's central stress response system.
How It Works
Withanolides regulate the HPA axis, reducing cortisol levels and normalizing the stress response. Ashwagandha also acts as a GABA-mimetic (producing calming effects), modulates serotonin pathways, has antioxidant and anti-inflammatory properties, and supports thyroid hormone production. In men, it increases luteinizing hormone and testosterone production. Its adaptogenic action means it helps the body resist and recover from both physical and psychological stress.
Key Benefits
Stress Reduction
Multiple RCTs show significant reductions in cortisol levels (up to 30%) and perceived stress scores. One of the most evidence-backed natural stress relievers available.
Cognitive Enhancement
Improves attention, information processing speed, and both immediate and general memory in clinical studies. Neuroprotective through antioxidant activity.
Physical Performance
Studies show increased VO2 max, muscle strength, muscle recovery, and testosterone levels in men who supplement with ashwagandha.
Sleep Quality
The calming effects of ashwagandha improve sleep onset latency, sleep quality, and morning alertness without next-day grogginess.
Dosing Guide
Ashwagandha Tincture
500mg ashwagandha extract daily
JGO's Hemp+Ashwagandha tincture combines 500mg of each. Best taken in the evening.
Safety & Interactions
Generally well-tolerated with an excellent safety profile in studies lasting up to 12 weeks. May cause mild GI discomfort in some individuals. Avoid during pregnancy. Those with autoimmune conditions or thyroid disorders should consult a healthcare provider.
Known Interactions
Frequently Asked Questions
How long does Ashwagandha take to work?
Some stress-relief benefits are felt within 1–2 weeks, but full adaptogenic effects (cortisol reduction, hormonal balance) build over 4–8 weeks of consistent use.
Can I take Ashwagandha with hemp extract?
Yes — this is one of the most popular adaptogenic combinations. JGO's Hemp+Ashwagandha tincture is specifically designed for this synergy.
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These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare provider before starting any supplement regimen.